February 8, 2018
February 8, 2018 —
Ever wonder why obese bodies burn less calories or why dieting often leads to a plateau in weight loss? In both cases the body is trying to defend its weight by regulating energy expenditure. In a paper publishing in Cell on February 8, University of California San Diego School of Medicine researchers identify the enzyme TANK-binding kinase 1 (TBK1) as a key player in the control of energy expenditure during both obesity and fasting.
February 7, 2018
February 7, 2018 —
Treating obese mice with catestatin (CST), a peptide naturally occurring in the body, showed significant improvement in glucose and insulin tolerance and reduced body weight, report University of California San Diego School of Medicine researchers.
January 11, 2018
January 11, 2018 —
UC San Diego Health and Eisenhower Health signed a five-year affiliation agreement to expand cancer services for residents of Coachella Valley. Starting in January 2018, as a member of the UC San Diego Health Cancer Network, patients of Eisenhower Health will have enhanced access to world-class cancer care, both at Eisenhower Lucy Curci Cancer Center and at UC San Diego Health.
December 20, 2017
December 20, 2017 —
Pharmaceutical interventions are routinely prescribed to help people quit smoking. However, a new study by University of California San Diego School of Medicine researchers suggests that, despite promising results in clinical trials, smoking cessation drugs alone may not be improving the chances of successful quitting among smokers in general.
December 18, 2017
December 18, 2017 —
An online survey of 900 consumers of three of the United States’ most popular cigarette brands suggests that adopting standardized cigarette packing may reduce consumers’ misconceptions that some cigarettes are less harmful than others, reports a team of researchers led by University of California San Diego School of Medicine and published in BMJ Tobacco Control.
December 11, 2017
December 11, 2017 —
Rare stem-like tumor cells play a critical role in the spread of breast cancer, but a vulnerability in the pathway that powers them offers a strategy to target these cells using existing drugs before metastatic disease occurs, report University of California San Diego School of Medicine and Moores Cancer Center researchers.
November 30, 2017
November 30, 2017 —
Glioblastoma, the most common and aggressive form of brain cancer, typically fails to respond to treatment or rapidly becomes drug resistant. In a paper published online in the journal Cancer Cell on November 30, University of California San Diego School of Medicine researchers identified a strategy that pinpoints a genetically distinct subpopulation of patients with glioblastoma that is particularly sensitive to drugs like cilengitide that target a cell adhesion receptor known as integrin αvβ3.
November 27, 2017
November 27, 2017 —
A team of University of California San Diego School of Medicine and Moores Cancer Center researchers studying new drugs designed to break resistance to cancer immunotherapy has been awarded a V Foundation for Cancer Research translational grant of $600,000 over three years.
November 14, 2017
November 14, 2017 —
Primary liver cancer is now the second leading cause of cancer-related death worldwide, and its incidences and mortality are increasing rapidly in the United Stated. In late stages of the malignancy, there are no effective treatments or drugs. However, an unexpected finding made by a team of University of California San Diego School of Medicine researchers sheds light on the development of a new strategy for prevention of liver cancer.
November 6, 2017
November 6, 2017 —
The five University of California medical centers, including Moores Cancer Center at UC San Diego Health, have joined together to recruit 100,000 women in California to be part of WISDOM: a clinical trial to uncover whether annual mammograms are the best way to screen for breast cancer, or whether a more personalized approach could deliver better results.
